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Anti-Human NGFR/TNFRSF16/p75NTR Polyclonal Antibody (HY350014)

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Aperçu
Numéro de catalogueHY350014
Description
Anti-Human NGFR/TNFRSF16/p75NTR Polyclonal Antibody (HY350014) is a rabbit polyclonal antibody detecting NGFR/TNFRSF16/p75NTR in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human CD271/NGF (Gly50-Glu190).
Cible CD271, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR, NGF receptor, NGFR, TNFRSF16, Tumor necrosis factor receptor superfamily member 16, p75 ICD
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Numéro d'accès P08138
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

Tumor necrosis factor receptor superfamily member 16 (CD271/NGFR) is a ~45 kDa protein. Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA.

1. Glerup, S. et al. (2014) Neuron 82, 1074-87. PMID: 24908487
2. Lin, Z. et al. (2015) eLife 4, e11692. PMID: 26646181
3. Baeza-Raja, B. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 10221-34. PMID: 23785138
4. Li, H. et al. (2012) Science China. Life sciences 55, 367-74. PMID: 22566094
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human NGFR/TNFRSF16/p75NTR Polyclonal Antibody

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