

| Каталожный номер | HV464043 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R) (HV464043) is a human monoclonal antibody detecting IL-23R in ELISA, FCM. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||
| Применения | ELISA, FCM | ||||
| Хозяинский вид | Human | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG1, kappa | ||||
| ID клона | Schering patent anti-IL-23R | ||||
| Проверенные приложения | FCM | ||||
| Цель | IL-23 receptor, IL-23R, IL23R, Interleukin-23 receptor | ||||
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q5VWK5 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Interleukin-23 receptor (IL23R) is a ~73 kDa protein. Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. | ||||
| Примечание | For research use only. |

Flow-cytometry using anti-human IL-23R antibody. HEK293 Transtected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IL-23R monoclonal antibody (Catalog HV464043, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.




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