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Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R) (HV464043)

Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R)
Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R)
Цена(USD): --
Спецификация:
  • 50ug
  • 100ug
  • 1mg
Количество:
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  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV464043
Описание
Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R) (HV464043) is a human monoclonal antibody detecting IL-23R in ELISA, FCM. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, FCM
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1, kappa
ID клонаSchering patent anti-IL-23R
Проверенные приложения FCM
Цель IL-23 receptor, IL-23R, IL23R, Interleukin-23 receptor
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q5VWK5
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Interleukin-23 receptor (IL23R) is a ~73 kDa protein. Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

Примечание For research use only.
Изображения
  • Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R)

    Flow cytometry

    Flow-cytometry using anti-human IL-23R antibody. HEK293 Transtected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IL-23R monoclonal antibody (Catalog HV464043, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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