

| Каталожный номер | HB070013 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-Human TNF RII/TNFRSF1B Recombinant Antibody (LbL-019) (HB070013) is a human monoclonal antibody detecting TNF RII/TNFRSF1B in ELISA. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Human | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG1, kappa | ||||
| ID клона | LbL-019 | ||||
| Цель | CD120b, Etanercept, TBP-2, TBPII, TNF-R2, TNF-RII, TNFBR, TNFR-II, TNFR2, TNFRSF1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor superfamily member 1b, membrane form, Tumor necrosis factor receptor type II, Tumor necrosis factor-binding protein 2, p75, p80 TNF-alpha receptor | ||||
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P20333 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFR2) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity. | ||||
| Примечание | For research use only. |




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