Anti-Bat SL-CoV-WIV1 Spike Recombinant Antibody (SAA3050) (VK172013)

Name: Anti-Bat SL-CoV-WIV1 Spike Recombinant Antibody (SAA3050)
Brand: abinScience
SKU: VK172013
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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SDS

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Каталожный номер

VK172013

Описание

Anti-Bat SL-CoV-WIV1 Spike Recombinant Antibody (SAA3050) (VK172013) is a human monoclonal antibody detecting Spike in ELISA. Suitable for Bat SARS-like coronavirus WIV1 (Bat SL-CoV-WIV1).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Реактивность видов

Bat SARS-like coronavirus WIV1 (Bat SL-CoV-WIV1)

Применения

ELISA

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG

ID клона

SAA3050

Цель

E2, Peplomer protein, S, S glycoprotein, Spike glycoprotein, Spike protein S1, Spike protein S2, Spike protein S2'

Уровень эндотоксинов

< 10 EU/mg as determined by LAL method.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

U5WI05

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Spike glycoprotein (Spike Protein (Trimer)) is a ~141 kDa protein. Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2. When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell membrane. When S2/S2' has not been cleaved, binding to the receptor results in internalization of the virus by endocytosis using host TFRC and GRM2 and leading to fusion of the virion membrane with the host endosomal membrane. Alternatively, may use NRP1/NRP2 and integrin as entry receptors.

1. Hoffmann, M. et al. (2020) Cell 181, 271-280.e8. PMID: 32142651

2. Walls, AC. et al. (2020) Cell 181, 281-292.e6. PMID: 32155444

3. Cao, W. et al. (2021) Biophysical journal 120, 1011-1019. PMID: 33607086

4. Takeda, M. (2022) Microbiology and immunology 66, 15-23. PMID: 34561887

5. Wrapp, D. et al. (2020) Science (New York, N.Y.) 367, 1260-1263. PMID: 32075877

6. Ou, X. et al. (2020) Nature communications 11, 1620. PMID: 32221306

7. Wang, J. et al. (2021) Cell discovery 7, 119. PMID: 34903715

8. Wang, X. et al. (2023) Journal of virology 97, e0161122. PMID: 36779763

9. Daly, JL. et al. (2020) Science (New York, N.Y.) 370, 861-865. PMID: 33082294

10. Cantuti-Castelvetri, L. et al. (2020) Science (New York, N.Y.) 370, 856-860. PMID: 33082293

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Bat SL-CoV-WIV1 Spike Recombinant Antibody (SAA3050).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Bat SL-CoV-WIV1 Spike Recombinant Antibody (SAA3050) (VK172013)

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