Anti-Human Complement Factor B Reference Antibody (SAR443809, RUO) (HF634036)

Name: Anti-Human Complement Factor B Reference Antibody (SAR443809, RUO)
Brand: abinScience
SKU: HF634036
Price: 370 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

100ug
1mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HF634036

Описание

Anti-Human Complement Factor B Reference Antibody (SAR443809, RUO) (HF634036) is a human monoclonal antibody detecting Complement Factor B.

Реактивность видов

Human

Применения

ELISA, FCM, Functional assay

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG4, kappa

ID клона

SAR443809

Цель

BF, BFD, Ba, Bb, C3/C5 convertase, CFB, Complement factor B, Complement factor B Ba, Complement factor B Bb, EC:3.4.21.47, GBG, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Уровень эндотоксинов

< 10 EU/mg as determined by LAL method.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P00751

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..

Фон

Complement factor B (CFB) is a ~85 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases.

1. Pangburn, MK. et al. (1986) The Biochemical journal 235, 723-30. PMID: 3638964

2. Vogt, W. et al. (1978) Immunology 34, 29-40. PMID: 624565

3. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279

4. Vogel, CW. et al. (1982) The Journal of biological chemistry 257, 8292-9. PMID: 6919543

5. Hourcade, DE. et al. (1998) The Journal of biological chemistry 273, 25996-6000. PMID: 9748277

6. Niemann, MA. et al. (1980) Biochemistry 19, 1576-83. PMID: 6769474

Примечание

For research use only. Not suitable for clinical or therapeutic use.

Изображения

Ссылки

Даташит

Anti-Human Complement Factor B Reference Antibody (SAR443809, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human Complement Factor B Reference Antibody (SAR443809, RUO) (HF634036)

Обзор

Изображения

Ссылки

Даташит

SDS