Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1) (HX905023)

Name: Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1)
Brand: abinScience
SKU: HX905023
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HX905023

Описание

Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1) (HX905023) is a human monoclonal antibody detecting SLC16A1/MCT1 in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG1, kappa

ID клона

Immunometabolism patent anti-MCT1

Цель

MCT 1, MCT1, Monocarboxylate transporter 1, SLC16A1, Solute carrier family 16 member 1

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P53985

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Monocarboxylate transporter 1 (SLC16A1/MCT1) is a ~53 kDa protein. Bidirectional proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH. The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate. MCT1 is a major lactate exporter. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

1. Pullen, TJ. et al. (2012) Diabetes 61, 1719-25. PMID: 22522610

2. Lengacher, S. et al. (2013) PloS one 8, e82505. PMID: 24367518

3. Reddy, A. et al. (2020) Cell 183, 62-75.e17. PMID: 32946811

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа