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| カタログ番号 | HW328076 |
|---|---|
| 説明 | |
| 種反応性 | Human |
| アプリケーション | ELISA, FCM, Functional assay |
| クローン性 | Monoclonal |
| アイソタイプ | GLP1-exendin 4-Fc |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | GCG, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP-2, GRPP, Glicentin, Glicentin-related polypeptide, Glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, Incretin hormone, OXM, OXY, Oxyntomodulin, Pro-glucagon, Exenatide, Exendin-4 |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P01275 & P26349 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. |
| 別名 | CAS: 3069923-11-8 |
| 背景 | Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. 1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722 2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095 3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125 4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449 5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895 6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285 7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
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