Anti-Human CD35 Reference Antibody (Ledacocept, RUO) (HB625016)

Name: Anti-Human CD35 Reference Antibody (Ledacocept, RUO)
Brand: abinScience
SKU: HB625016
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Каталожный номер	HB625016
Описание	Anti-Human CD35 Reference Antibody (Ledacocept, RUO) (HB625016) is a monoclonal antibody detecting CD35.
Реактивность видов	Human
Применения	ELISA, FCM, Functional assay
Клоональность	Monoclonal
Изотип	CD35
Система экспрессии	Mammalian cells
Характер	Recombinant
Цель	C3BR, C3b/C4b receptor, CD35, CR1, Complement receptor type 1
Уровень эндотоксинов	< 10 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P17927
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Альтернативные названия	CAS: 3083227-23-7
Фон	Complement receptor type 1 (CD35/CR1) is a ~223 kDa protein. Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages. Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation. Also acts in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Also plays a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells. 1. Schifferli, JA. et al. (1988) Journal of immunology (Baltimore, Md. : 1950) 140, 899-904. PMID: 2963069 2. Klickstein, LB. et al. (1988) The Journal of experimental medicine 168, 1699-717. PMID: 2972794 3. Krych, M. et al. (1994) The Journal of biological chemistry 269, 13273-8. PMID: 8175757 4. Török, K. et al. (2015) Immunology letters 164, 117-24. PMID: 25742728
Примечание	For research use only. Not suitable for clinical or therapeutic use.

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Anti-Human CD35 Reference Antibody (Ledacocept, RUO).pdf

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Anti-Human CD35 Reference Antibody (Ledacocept, RUO) (HB625016)

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