

| Каталожный номер | HY242016 |
|---|---|
| Описание |
Anti-Human Calprotectin/S100A8 & S100A9 Reference Antibody (Murunprubart, RUO) (HY242016) is a human monoclonal antibody detecting Calprotectin.
|
| Реактивность видов | Human |
| Применения | ELISA, FCM, Functional assay |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG4, lambda2 |
| Цель | CAGA, CFAG, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MRP-8, MRP8, Migration inhibitory factor-related protein 8, Protein S100-A8, S100 calcium-binding protein A8, S100A8, Urinary stone protein band A, p8, CAGB, CFAG, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, MRP-14, MRP14, Migration inhibitory factor-related protein 14, Protein S100-A9, S100 calcium-binding protein A9, S100A9, p14 |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P05109 & P06702 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. |
| Альтернативные названия | CAS: 3060352-02-2 |
| Фон | Protein S100-A8 (Calprotectin (S100A8/9)) is a ~10 kDa protein. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69. 1. Lin, CR. et al. (2015) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 29, 5006-17. PMID: 26296369 |
| Примечание | For research use only. |
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