Anti-Human Siglec-10 Reference Antibody (Tasafustobart, RUO) (HV244026)

Name: Anti-Human Siglec-10 Reference Antibody (Tasafustobart, RUO)
Brand: abinScience
SKU: HV244026
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Обзор

Каталожный номер	HV244026
Описание	Anti-Human Siglec-10 Reference Antibody (Tasafustobart, RUO) (HV244026) is a human monoclonal antibody detecting Siglec-10.
Реактивность видов	Human
Применения	ELISA, FCM, Functional assay
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG4, kappa
Цель	SIGLEC10, SLG2, Sialic acid-binding Ig-like lectin 10, Siglec-10, Siglec-like protein 2
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q96LC7
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Альтернативные названия	CAS: 3082356-05-3
Фон	Sialic acid-binding Ig-like lectin 10 (SIGLEC10/SLG2) is a ~76 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, seems to act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Involved in negative regulation of B-cell antigen receptor signaling. 1. Munday, J. et al. (2001) The Biochemical journal 355, 489-97. PMID: 11284738 2. Kitzig, F. et al. (2002) Biochemical and biophysical research communications 296, 355-62. PMID: 12163025 3. Zhang, P. et al. (2015) The Journal of surgical research 194, 107-13. PMID: 25450598
Примечание	For research use only.

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Anti-Human Siglec-10 Reference Antibody (Tasafustobart, RUO).pdf

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