Anti-Human CD46 Recombinant Antibody (SRR0011) (HB735023)

Name: Anti-Human CD46 Recombinant Antibody (SRR0011)
Brand: abinScience
SKU: HB735023
Price: 191 USD
Availability: InStock

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50ul
100ul

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Número de catálogo	HB735023
Descripción	Anti-Human CD46 Recombinant Antibody (SRR0011) (HB735023) is a rabbit monoclonal antibody detecting CD46 in FCM, WB. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Reactividad de especies	Human
Aplicaciones	FCM, WB
Especie huésped	Rabbit
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	SRR0011
Aplicaciones probadas	FCM, WB
Objetivo	CD46, MCP, MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
Nivel de endotoxinas	< 10 EU/mg as determined by LAL method.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P15529
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Nota	For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-CD46monoclonal antibody at 1 ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: HEK293T cell lysate
Flow cytometry

Flow-cytometry using anti-Human CD46 antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-Human CD46 monoclonal antibody (Catalog HB735023, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Rabbit IgG H&L Polyclonal Antibody, FITC (abinScience:TF690414) and cells analysed on a NovoCyte Flow Cytometer.

Referencias

Datasheet

Anti-Human CD46 Recombinant Antibody (SRR0011).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Anti-Human CD46 Recombinant Antibody (SRR0011) (HB735023)

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Imágenes

Referencias

Datasheet

SDS