Anti-Human CD46 Recombinant Antibody (SRR0011) (HB735023)

Name: Anti-Human CD46 Recombinant Antibody (SRR0011)
Brand: abinScience
SKU: HB735023
Price: 191 USD
Availability: InStock

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50ul
100ul

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Каталожный номер	HB735023
Описание	Anti-Human CD46 Recombinant Antibody (SRR0011) (HB735023) is a rabbit monoclonal antibody detecting CD46 in FCM, WB. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Реактивность видов	Human
Применения	FCM, WB
Хозяинский вид	Rabbit
Клоональность	Monoclonal
Изотип	IgG
ID клона	SRR0011
Проверенные приложения	FCM, WB
Цель	CD46, MCP, MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
Уровень эндотоксинов	< 10 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P15529
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Примечание	For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-CD46monoclonal antibody at 1 ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: HEK293T cell lysate
Flow cytometry

Flow-cytometry using anti-Human CD46 antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-Human CD46 monoclonal antibody (Catalog HB735023, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Rabbit IgG H&L Polyclonal Antibody, FITC (abinScience:TF690414) and cells analysed on a NovoCyte Flow Cytometer.

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Anti-Human CD46 Recombinant Antibody (SRR0011).pdf

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Formula

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Anti-Human CD46 Recombinant Antibody (SRR0011) (HB735023)

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