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Anti-Human CRACC/SLAMF7 Recombinant Antibody (HuLuc63) (HV217013)

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Спецификация:
  • 50ug
  • 100ug
  • 1mg
Количество:
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Обзор
Каталожный номерHV217013
Описание
Anti-Human CRACC/SLAMF7 Recombinant Antibody (HuLuc63) (HV217013) is a monoclonal antibody detecting CRACC/SLAMF7 in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Реактивность видовHuman
ПримененияELISA
КлоональностьMonoclonal
ИзотипscFv-His
ID клонаHuLuc63
Цель CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CD319, CRACC, CS1, Membrane protein FOAP-12, Novel Ly9, Protein 19A, SLAM family member 7, SLAMF7
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q9NQ25
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

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Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

SLAM family member 7 (CD319/SLAMF7) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B.

1. Bouchon, A. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 5517-21. PMID: 11698418
2. Tassi, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7996-8002. PMID: 16339536
3. Murphy, JJ. et al. (2002) The Biochemical journal 361, 431-6. PMID: 11802771
4. Kim, JR. et al. (2013) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 62, 765-72. PMID: 23695528
Примечание For research use only.
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Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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