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| カタログ番号 | HB237014 | ||||||||
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| 説明 |
Anti-MGMT Polyclonal Antibody (HB237014) is a rabbit polyclonal antibody detecting MGMT in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| アイソタイプ | IgG | ||||||||
| クローン性 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human MGMT (Met1-Asn207). | ||||||||
| ターゲット | MGMT, 6-O-methylguanine-DNA methyltransferase, Methylated-DNA--protein-cysteine methyltransferase, O-6-methylguanine-DNA-alkyltransferase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P16455 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Methylated-DNA--protein-cysteine methyltransferase (MGMT) is a ~21 kDa protein. Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-MGMT polyclonal antibody at 1ug/mL on recombinant MGMT (Catalog No. HB237012).
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