Anti-Human CD14 Recombinant Antibody (18D11), APC-Cy7 (HY038457)

Name: Anti-Human CD14 Recombinant Antibody (18D11), APC-Cy7
Brand: abinScience
SKU: HY038457
Price: 435 USD
Availability: InStock

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Каталожный номер	HY038457
Описание	Anti-Human CD14 Recombinant Antibody (18D11), APC-Cy7 (HY038457) is a mouse monoclonal antibody detecting CD14 in FCM. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●APC-Cy7 Conjugated — Ready for direct detection without secondary antibody.
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1
ID клона	18D11
Конъюгация	APC-Cy7
Цель	CD14, Monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14, membrane-bound form, Monocyte differentiation antigen CD14, urinary form, My23 antigen, Myeloid cell-specific leucine-rich glycoprotein
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P08571
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein,CD14,Monocyte differentiation antigen CD14) is a ~40 kDa protein. Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-). 1. Wright, SD. et al. (1990) Science (New York, N.Y.) 249, 1431-3. PMID: 1698311 2. Kelley, SL. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 1304-11. PMID: 23264655 3. Tsukamoto, H. et al. (2010) International immunology 22, 271-80. PMID: 20133493 4. Murakami, K. et al. (2012) FEBS letters 586, 319-24. PMID: 22265692 5. Haziot, A. et al. (1996) Immunity 4, 407-14. PMID: 8612135 6. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211 7. Estruch, M. et al. (2013) Atherosclerosis 229, 356-62. PMID: 23880187
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD14 Recombinant Antibody (18D11), APC-Cy7.pdf

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Anti-Human CD14 Recombinant Antibody (18D11), APC-Cy7 (HY038457)

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