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Anti-Mouse CD8a/Lyt2 Antibody (53-6.72) (MF815607)

Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)
Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)
Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)
Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)
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概要
カタログ番号MF815607
説明
Anti-Mouse CD8a/Lyt2 Antibody (53-6.72) [53-6.72] (MF815607) is a rat monoclonal antibody detecting CD8a in Blocking, FCM, IF, WB. Suitable for Mouse.
Highlights
  • Multi-Application — Validated across multiple applications.
  • Flow Cytometry — Validated for flow cytometry applications.
種反応性Mouse
アプリケーションBlocking, FCM, IF, WB
宿主種Rat
アイソタイプIgG2a, kappa
クローンID53-6.72
クローン性 Monoclonal
ターゲット T-cell surface glycoprotein CD8 alpha chain, CD8a, T-lymphocyte differentiation antigen T8/Leu-2, MAL, CD8A, CD8
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P01731
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

注意事項 For research use only.
イメージ
  • Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)

  • Anti-Mouse CD8a/Lyt2 Antibody (53-6.72)

    Bioactivity

    Detects recombinant mouse CD8A (Catalog No: MF815011) in indirect ELISA

参考文献
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