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Anti-Human CD303/CLEC4C Antibody (122A2), FITC (HV560117)

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概要
カタログ番号HV560117
説明
Anti-Human CD303/CLEC4C Antibody (122A2), FITC [122A2] (HV560117) is a mouse monoclonal antibody detecting CLEC4C in FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
  • Fluorescent Label — Direct conjugate for streamlined workflows.
種反応性Human
アプリケーションFCM
宿主種Mouse
アイソタイプIgG1, kappa
クローンID122A2
抱合FITC
クローン性 Monoclonal
ターゲット CLEC4C, C-type lectin superfamily member 7, CLECSF11, C-type lectin domain family 4 member C, Dendritic lectin, CD303, DLEC, HECL, Blood dendritic cell antigen 2, BDCA-2, BDCA2, CLECSF7
エンドトキシンレベル Please contact with the lab for this information.
アクセッション番号 Q8WTT0
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

C-type lectin domain family 4 member C (CD303/CLEC4C) is a ~25 kDa protein. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells.

1. Dzionek, A. et al. (2001) The Journal of experimental medicine 194, 1823-34. PMID: 11748283
2. Riboldi, E. et al. (2011) The Journal of biological chemistry 286, 35329-35333. PMID: 21880719
3. Jégouzo, SA. et al. (2015) The Journal of biological chemistry 290, 16759-71. PMID: 25995448
注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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参考文献
Formula
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