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| カタログ番号 | RB941247 |
|---|---|
| 説明 |
Anti-Rat VEGFA Antibody (SAA0447), PerCP [SAA0447] (RB941247) is a mouse monoclonal antibody detecting VEGFA in ELISA, FCM. Suitable for Rat.
Highlights
|
| 種反応性 | Rat |
| アプリケーション | ELISA, FCM |
| 宿主種 | Mouse |
| アイソタイプ | IgG2a, kappa |
| クローンID | SAA0447 |
| 抱合 | PerCP |
| クローン性 | Monoclonal |
| ターゲット | Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A |
| エンドトキシンレベル | Please contact with the lab for this information. |
| アクセッション番号 | P16612 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Vascular endothelial growth factor A (VEGFA) is a ~25 kDa protein. Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. VEGFA is the therapeutic target of bevacizumab (Avastin). |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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