

| Каталожный номер | HF877011 |
|---|---|
| Описание |
Human PDGF-B Recombinant Protein (Tag Free) (HF877011) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| Система экспрессии | Mammalian cells |
| Номер доступа | P01127 |
| Длина белка | Ser82-Thr190 |
| Применения | ELISA, Functional assay |
| Виды | Homo sapiens (Human) |
| Биологическая активность | Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is ≤5 ng/mL. |
| Характер | Recombinant |
| Уровень эндотоксинов | <0.01 EU/ug |
| Чистота | >95% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 12.2 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a 0.22 μm-filtered solution containing PBS,5% Mannitol, 0.01% Tween 80, pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | Becaplermin, PDGF subunit B, PDGF-2, PDGF2, PDGFB, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, Proto-oncogene c-Sis, SIS |
| Фон | Platelet-derived growth factor subunit B (PDGFB) is a ~27 kDa protein. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. 1. Vanlandewijck, M. et al. (2015) PloS one 10, e0143407. PMID: 26599395 |
| Примечание | For research use only |




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