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| カタログ番号 | VK521030 |
|---|---|
| 説明 |
InVivoMAb Anti-Nipah virus/NiV Prefusion Antibody (1A9) [1A9] (VK521030) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization. Suitable for Nipah virus.
|
| 種反応性 | Nipah virus |
| アプリケーション | ELISA, Neutralization |
| 宿主種 | Human |
| アイソタイプ | IgG1 |
| クローンID | 1A9 |
| クローン性 | Monoclonal |
| ターゲット | Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q9IH63 |
| RRID | InVivoMAb Anti-Nipah virus/NiV Prefusion Antibody (1A9) (abinScience Cat# VK521030, RRID:AB_3727180) |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Fusion glycoprotein F0 is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-Nipah virus/NiV Prefusion Antibody (1A9).
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