



| Каталожный номер | AY286213 |
|---|---|
| Описание |
Anti-Trastuzumab Neutralizing Recombinant Antibody (SAA2826) (AY286213) is a rabbit monoclonal antibody detecting Trastuzumab in ELISA. Suitable for General.
Highlights
|
| Реактивность видов | General |
| Применения | ELISA |
| Хозяинский вид | Rabbit |
| Клоональность | Monoclonal |
| Изотип | IgG |
| ID клона | SAA2826 |
| Иммуноген | Trastuzumab |
| Уровень эндотоксинов | < 10EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | CAS: 180288-69-1 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Receptor tyrosine-protein kinase erbB-2 (Trastuzumab) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. |
| Примечание | For research use only. |




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