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Research Grade Docaravimab (VK584016)

Research Grade Docaravimab
Research Grade Docaravimab
価格(USD): $
スペック:
  • 100ug
  • 1mg
数量:
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  • 概要

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  • データシート

概要
カタログ番号VK584016
説明
Docaravimab (VK584016) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Rabies virus (RABV)
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Mouse
アイソタイプIgG2b, kappa
発現システム Mammalian Cells
クローン性 Monoclonal
ターゲット G/Glycoprotein
エンドトキシンレベル Please contact the lab for this information.
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P03524
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
別名2247196-23-0
背景

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
イメージ
  • Research Grade Docaravimab

    Bioactivity

    Detects Recombinant RABV G/Glycoprotein, C-His (Cat No.: VK584011) in indirect ELISA.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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