

| カタログ番号 | VK584016 |
|---|---|
| 説明 |
Docaravimab (VK584016) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Rabies virus (RABV) |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Mouse |
| アイソタイプ | IgG2b, kappa |
| 発現システム | Mammalian Cells |
| クローン性 | Monoclonal |
| ターゲット | G/Glycoprotein |
| エンドトキシンレベル | Please contact the lab for this information. |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P03524 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 別名 | 2247196-23-0 |
| 背景 | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |

Detects Recombinant RABV G/Glycoprotein, C-His (Cat No.: VK584011) in indirect ELISA.


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