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Research Grade Miromavimab
Research Grade Miromavimab
Prix(USD) : $
Spécification :
  • 100ug
  • 1mg
Nombre :
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Aperçu
Numéro de catalogueVK584026
Description
Miromavimab (VK584026) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesRabies virus (RABV)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteMouse
IsotypeIgG1, kappa
Système d'expression Mammalian Cells
Clonalité Monoclonal
Cible G/Glycoprotein
Niveau d'endotoxines Please contact the lab for this information.
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P03524
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Noms alternatifsM777-16-3, 2247163-73-9
Contexte

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Miromavimab

    Bioactivity

    Detects G/Glycoprotein in indirect ELISAs.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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