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Research Grade Delpacibart (HY036036)

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Research Grade Delpacibart

Research Grade Delpacibart

Research Grade Delpacibart

Research Grade Delpacibart

Research Grade Delpacibart

Research Grade Delpacibart

価格(USD): $

スペック:

100ug
1mg

数量:

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概要
イメージ
参考文献
データシート

概要

カタログ番号	HY036036
説明	Delpacibart (HY036036) is a research-grade recombinant antibody targeting CD71. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG1-kappa
発現システム	Mammalian Cells
クローン性	Monoclonal
ターゲット	Transferrin receptor protein 1, TfR1, T9, Trfr, p90, CD71, TFRC, TfR, sTfR, TR
エンドトキシンレベル	Please contact the lab for this information.
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P02786
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
別名	2653183-68-5, 2653183-66-3
背景	Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. 1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738 2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

Bioactivity

Detects Recombinant Human CD71/TFRC Protein, C-His (Cat No.: HY036011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD71/TFRC monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD71/TFRC (Catalog No: HY036011)
Lane 2: negative control
SDS-PAGE

SDS-PAGE for Research Grade Delpacibart

参考文献

データシート

Research Grade Delpacibart.pdf

Formula

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Research Grade Delpacibart