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Research Grade Volrustomig (HS870396)

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Research Grade Volrustomig

Research Grade Volrustomig

Research Grade Volrustomig

Research Grade Volrustomig

価格(USD): $

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100ug
1mg

数量:

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概要
イメージ
参考文献
データシート

概要

カタログ番号	HS870396
説明	Volrustomig (HS870396) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG1-kappa/kappa-lambda
発現システム	Mammalian Cells
クローン性	Monoclonal
ターゲット	Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279, CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4
エンドトキシンレベル	Please contact the lab for this information.
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q15116 & P16410
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
別名	2407760-40-9
背景	Danvilostomig is an anti-CTLA4/PDCD1 monoclonal antibody. • Cancer immunotherapy using checkpoint blockade., PMID:29567705 • The blockade of immune checkpoints in cancer immunotherapy., PMID:22437870 • Immune-related adverse events of checkpoint inhibitors., PMID:32382051 • Immune Checkpoint Blockade in Cancer Therapy., PMID:25605845 • Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy., PMID:29256113 • Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination., PMID:27141885 • Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints., PMID:30184160 • Tumour- and class-specific patterns of immune-related adverse events of immune checkpoint inhibitors: a systematic review., PMID:28945858 • Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer., PMID:34088360 • Fundamental Mechanisms of Immune Checkpoint Blockade Therapy., PMID:30115704
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

Bioactivity

Detects recombinant human PD1 (Cat No.: HS870021) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD152/CTLA4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD152/CTLA4 (Catalog No: HB651011)
Lane 2: negative control

参考文献

データシート

Research Grade Volrustomig.pdf

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Research Grade Volrustomig