

| Numéro de catalogue | MB957012 |
|---|---|
| Description |
Recombinant Mouse AOAH Protein, N-His (MB957012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | O35298 |
| Longueur de protéine | Ala22-His574 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Mus musculus (Mouse) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | Acyloxyacyl hydrolase, Acyloxyacyl hydrolase large subunit, Acyloxyacyl hydrolase small subunit, Aoah, EC:3.1.1.77 |
| Contexte | Acyloxyacyl hydrolase is a ~65 kDa protein. Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPS). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria. 1. Lu, M. et al. (2003) The Journal of experimental medicine 197, 1745-54. PMID: 12810692 2. Feulner, JA. et al. (2004) Infection and immunity 72, 3171-8. PMID: 15155618 3. Shao, B. et al. (2007) The Journal of biological chemistry 282, 13726-35. PMID: 17322564 4. Ojogun, N. et al. (2009) The Journal of infectious diseases 200, 1685-93. PMID: 19860560 5. Zou, B. et al. (2017) PLoS pathogens 13, e1006436. PMID: 28622363 6. Lu, M. et al. (2008) Cell host & microbe 4, 293-302. PMID: 18779055 |
| Note | For research use only |
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