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Mouse AOAH Recombinant Protein (N-His) (MB957012)

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概要
カタログ番号MB957012
説明
Recombinant Mouse AOAH Protein, N-His (MB957012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
発現システムE. coli
アクセッション番号O35298
タンパク質長Ala22-His574
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Acyloxyacyl hydrolase, Acyloxyacyl hydrolase large subunit, Acyloxyacyl hydrolase small subunit, Aoah, EC:3.1.1.77
背景

Acyloxyacyl hydrolase is a ~65 kDa protein. Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPS). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria.

1. Lu, M. et al. (2003) The Journal of experimental medicine 197, 1745-54. PMID: 12810692
2. Feulner, JA. et al. (2004) Infection and immunity 72, 3171-8. PMID: 15155618
3. Shao, B. et al. (2007) The Journal of biological chemistry 282, 13726-35. PMID: 17322564
4. Ojogun, N. et al. (2009) The Journal of infectious diseases 200, 1685-93. PMID: 19860560
5. Zou, B. et al. (2017) PLoS pathogens 13, e1006436. PMID: 28622363
6. Lu, M. et al. (2008) Cell host & microbe 4, 293-302. PMID: 18779055
注意事項 For research use only
イメージ
参考文献
Formula
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