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| カタログ番号 | MC338012 |
|---|---|
| 説明 |
Recombinant Mouse FGL1 Protein, N-His (MC338012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q71KU9 |
| タンパク質長 | Ala83-Ile314 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Fgl1, Fibrinogen-like protein 1, Fibrinogen-related protein 1, Liver fibrinogen-related protein-1, Mfire-1, Mfire1, Mfrep-1 |
| 背景 | Fibrinogen-like protein 1 is a ~36 kDa protein. Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a ligand of LAG3. LAG3-binding initiates a signaling that inhibits the T-cell receptor (TCR) in the immunological synapse, preventing T-cell activation. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes. 1. Wang, J. et al. (2019) Cell 176, 334-347.e12. PMID: 30580966 |
| 注意事項 | For research use only |
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