Mouse ALDH1A1 Recombinant Protein (N-His) (MF669012)

Name: Mouse ALDH1A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MF669012
Price: 211 USD
Availability: InStock

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Número de catálogo	MF669012
Descripción	Recombinant Mouse ALDH1A1 Protein, N-His (MF669012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P24549
Longitud de proteína	Lys36-Gly271
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Ahd-2, Ahd2, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Aldh1, Aldh1a1, EC:1.2.1.19, EC:1.2.1.28, EC:1.2.1.3, EC:1.2.1.36, RALDH 1, RalDH1, Retinal dehydrogenase 1
Fondo	Aldehyde dehydrogenase 1A1 is a ~54 kDa protein. Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid. Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid. This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (Probable). Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic. By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification. 1. Molotkov, A. et al. (2003) The Journal of biological chemistry 278, 36085-90. PMID: 12851412 2. Lassen, N. et al. (2007) The Journal of biological chemistry 282, 25668-76. PMID: 17567582 3. Kim, JI. et al. (2015) Science (New York, N.Y.) 350, 102-6. PMID: 26430123
Nota	For research use only

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Datasheet

Mouse ALDH1A1 Recombinant Protein (N-His).pdf

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