Mouse ALDH1A1 Recombinant Protein (N-His) (MF669012)

Name: Mouse ALDH1A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MF669012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MF669012
Description	Recombinant Mouse ALDH1A1 Protein, N-His (MF669012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P24549
Longueur de protéine	Lys36-Gly271
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Ahd-2, Ahd2, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Aldh1, Aldh1a1, EC:1.2.1.19, EC:1.2.1.28, EC:1.2.1.3, EC:1.2.1.36, RALDH 1, RalDH1, Retinal dehydrogenase 1
Contexte	Aldehyde dehydrogenase 1A1 is a ~54 kDa protein. Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid. Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid. This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (Probable). Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic. By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification. 1. Molotkov, A. et al. (2003) The Journal of biological chemistry 278, 36085-90. PMID: 12851412 2. Lassen, N. et al. (2007) The Journal of biological chemistry 282, 25668-76. PMID: 17567582 3. Kim, JI. et al. (2015) Science (New York, N.Y.) 350, 102-6. PMID: 26430123
Note	For research use only

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Mouse ALDH1A1 Recombinant Protein (N-His).pdf

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