Mouse ALDH1A1 Recombinant Protein (N-His) (MF669012)

Name: Mouse ALDH1A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: MF669012
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	MF669012
Описание	Recombinant Mouse ALDH1A1 Protein, N-His (MF669012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P24549
Длина белка	Lys36-Gly271
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Mus musculus (Mouse)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Ahd-2, Ahd2, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Aldh1, Aldh1a1, EC:1.2.1.19, EC:1.2.1.28, EC:1.2.1.3, EC:1.2.1.36, RALDH 1, RalDH1, Retinal dehydrogenase 1
Фон	Aldehyde dehydrogenase 1A1 is a ~54 kDa protein. Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid. Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid. This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (Probable). Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic. By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification. 1. Molotkov, A. et al. (2003) The Journal of biological chemistry 278, 36085-90. PMID: 12851412 2. Lassen, N. et al. (2007) The Journal of biological chemistry 282, 25668-76. PMID: 17567582 3. Kim, JI. et al. (2015) Science (New York, N.Y.) 350, 102-6. PMID: 26430123
Примечание	For research use only

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Mouse ALDH1A1 Recombinant Protein (N-His).pdf

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Formula

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