Mouse ZBED6 Recombinant Protein (N-His) (ME017012)

Name: Mouse ZBED6 Recombinant Protein (N-His)
Brand: abinScience
SKU: ME017012
Price: 211 USD
Availability: InStock

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Número de catálogo	ME017012
Descripción	Recombinant Mouse ZBED6 Protein, N-His (ME017012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	D2EAC2
Longitud de proteína	Ser480-Asn779
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	MGR, Muscle growth regulator, Zbed6, Zinc finger BED domain-containing protein 6
Fondo	Zinc finger BED domain-containing protein 6 is a ~109 kDa protein. Transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3', transcription regulation may be tissue-specific. Regulates the expression of target genes such as: IGF2, PGAP6/TMEM8, ENHO, and PIANP. Acts as a transcriptional repressor of growth factor IGF2, thereby negatively regulating postnatal growth of muscles and internal organs, especially in females. Negatively regulates myoblast differentiation and myoblast mitochondrial activity via its regulation of IGF2 transcription. Negatively regulates the cell cycle of myoblasts, potentially via transcriptional regulation of the E2F family of transcription factors such as: E2F1 and E2F2. 1. Markljung, E. et al. (2009) PLoS biology 7, e1000256. PMID: 20016685 2. Butter, F. et al. (2010) EMBO reports 11, 305-11. PMID: 20134481 3. Wang, X. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15997-6002. PMID: 24043816 4. Younis, S. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E2048-E2057. PMID: 29440408 5. Younis, S. et al. (2020) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34, 10250-10266. PMID: 32557799 6. Wang, X. et al. (2016) Scientific reports 6, 19006. PMID: 26750727
Nota	For research use only

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Datasheet

Mouse ZBED6 Recombinant Protein (N-His).pdf

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Formula

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Stock Solution

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Working Solution

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