Mouse ZBED6 Recombinant Protein (N-His) (ME017012)

Name: Mouse ZBED6 Recombinant Protein (N-His)
Brand: abinScience
SKU: ME017012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	ME017012
Описание	Recombinant Mouse ZBED6 Protein, N-His (ME017012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	D2EAC2
Длина белка	Ser480-Asn779
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Mus musculus (Mouse)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	MGR, Muscle growth regulator, Zbed6, Zinc finger BED domain-containing protein 6
Фон	Zinc finger BED domain-containing protein 6 is a ~109 kDa protein. Transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3', transcription regulation may be tissue-specific. Regulates the expression of target genes such as: IGF2, PGAP6/TMEM8, ENHO, and PIANP. Acts as a transcriptional repressor of growth factor IGF2, thereby negatively regulating postnatal growth of muscles and internal organs, especially in females. Negatively regulates myoblast differentiation and myoblast mitochondrial activity via its regulation of IGF2 transcription. Negatively regulates the cell cycle of myoblasts, potentially via transcriptional regulation of the E2F family of transcription factors such as: E2F1 and E2F2. 1. Markljung, E. et al. (2009) PLoS biology 7, e1000256. PMID: 20016685 2. Butter, F. et al. (2010) EMBO reports 11, 305-11. PMID: 20134481 3. Wang, X. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15997-6002. PMID: 24043816 4. Younis, S. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E2048-E2057. PMID: 29440408 5. Younis, S. et al. (2020) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34, 10250-10266. PMID: 32557799 6. Wang, X. et al. (2016) Scientific reports 6, 19006. PMID: 26750727
Примечание	For research use only

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Mouse ZBED6 Recombinant Protein (N-His).pdf

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