Mouse PDPN/Podoplanin Recombinant Protein (N-His) (MV106022)

Name: Mouse PDPN/Podoplanin Recombinant Protein (N-His)
Brand: abinScience
SKU: MV106022
Price: 211 USD
Availability: InStock

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Número de catálogo	MV106022
Descripción	Recombinant Mouse PDPN Protein, N-His (MV106022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q62011
Longitud de proteína	Gly23-Leu141
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	14.76 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	E11, Glycoprotein 38, Gp38, OTS-8, Ots8, PA2.26 antigen, Pdpn, Podoplanin, Transmembrane glycoprotein E11
Fondo	Podoplanin is a ~18 kDa protein. Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation. Interaction with CD9, on the contrary, attenuates platelet aggregation and pulmonary metastasis induced by PDPN. Mediates effects on cell migration and adhesion through its different partners. Through MSN or EZR interaction promotes epithelial-mesenchymal transition (EMT) leading to ERZ phosphorylation and triggering RHOA activation leading to cell migration increase and invasiveness. 1. Kato, Y. et al. (2003) The Journal of biological chemistry 278, 51599-605. PMID: 14522983 2. Kaneko, M. et al. (2004) The Journal of biological chemistry 279, 38838-43. PMID: 15231832 3. Suzuki-Inoue, K. et al. (2007) The Journal of biological chemistry 282, 25993-6001. PMID: 17616532 4. Uhrin, P. et al. (2010) Blood 115, 3997-4005. PMID: 20110424 5. Astarita, JL. et al. (2015) Nature immunology 16, 75-84. PMID: 25347465 6. Scholl, FG. et al. (1999) Journal of cell science 112 ( Pt 24), 4601-13. PMID: 10574709 7. Ramirez, MI. et al. (2003) Developmental biology 256, 61-72. PMID: 12654292 8. Boucherot, A. et al. (2002) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 17, 978-84. PMID: 12032185
Nota	For research use only

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Datasheet

Mouse PDPN/Podoplanin Recombinant Protein (N-His).pdf

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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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