Mouse PDPN Recombinant Protein (N-His) (MV106022)

Name: Mouse PDPN Recombinant Protein (N-His)
Brand: abinScience
SKU: MV106022
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	MV106022
Описание	Recombinant Mouse PDPN Protein, N-His (MV106022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q62011
Длина белка	Gly23-Leu141
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Mus musculus (Mouse)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	E11, Glycoprotein 38, Gp38, OTS-8, Ots8, PA2.26 antigen, Pdpn, Podoplanin, Transmembrane glycoprotein E11
Фон	Podoplanin is a ~18 kDa protein. Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation. Interaction with CD9, on the contrary, attenuates platelet aggregation and pulmonary metastasis induced by PDPN. Mediates effects on cell migration and adhesion through its different partners. Through MSN or EZR interaction promotes epithelial-mesenchymal transition (EMT) leading to ERZ phosphorylation and triggering RHOA activation leading to cell migration increase and invasiveness. 1. Kato, Y. et al. (2003) The Journal of biological chemistry 278, 51599-605. PMID: 14522983 2. Kaneko, M. et al. (2004) The Journal of biological chemistry 279, 38838-43. PMID: 15231832 3. Suzuki-Inoue, K. et al. (2007) The Journal of biological chemistry 282, 25993-6001. PMID: 17616532 4. Uhrin, P. et al. (2010) Blood 115, 3997-4005. PMID: 20110424 5. Astarita, JL. et al. (2015) Nature immunology 16, 75-84. PMID: 25347465 6. Scholl, FG. et al. (1999) Journal of cell science 112 ( Pt 24), 4601-13. PMID: 10574709 7. Ramirez, MI. et al. (2003) Developmental biology 256, 61-72. PMID: 12654292 8. Boucherot, A. et al. (2002) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 17, 978-84. PMID: 12032185
Примечание	For research use only

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Mouse PDPN Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

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Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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