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| カタログ番号 | MX143022 |
|---|---|
| 説明 |
Recombinant Mouse CX3CL1 Protein, N-GST & C-His (MX143022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O35188 |
| タンパク質長 | Thr40-Lys102 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | ABCD-3, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Cx3c, Cx3cl1, FK, Fkn, Fractalkine, Neurotactin, Processed fractalkine, Scyd1, Small-inducible cytokine D1 |
| 背景 | Fractalkine is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. 1. Haskell, CA. et al. (1999) The Journal of biological chemistry 274, 10053-8. PMID: 10187784 2. Landsman, L. et al. (2009) Blood 113, 963-72. PMID: 18971423 3. Kanazawa, N. et al. (1999) European journal of immunology 29, 1925-32. PMID: 10382755 4. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350 |
| 注意事項 | For research use only |
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