

| Каталожный номер | MX158012 |
|---|---|
| Описание |
Recombinant Mouse UCP3 Protein, N-GST & C-His (MX158012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P56501 |
| Длина белка | Pro33-Ser73&Asp97-Arg116&Thr134-Trp179 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Mus musculus (Mouse) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | Putative mitochondrial transporter UCP3, Slc25a9, Solute carrier family 25 member 9, UCP 3, Ucp3, Uncoupling protein 3 |
| Фон | Putative mitochondrial transporter UCP3 is a ~33 kDa protein. Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity. 1. Gong, DW. et al. (2000) The Journal of biological chemistry 275, 16251-7. PMID: 10748195 2. Vidal-Puig, AJ. et al. (2000) The Journal of biological chemistry 275, 16258-66. PMID: 10748196 3. Macher, G. et al. (2018) Biochimica et biophysica acta. Biomembranes 1860, 664-672. PMID: 29212043 4. Cadenas, S. et al. (2002) The Journal of biological chemistry 277, 2773-8. PMID: 11707458 5. Lombardi, A. et al. (2010) The Journal of biological chemistry 285, 16599-605. PMID: 20363757 |
| Примечание | For research use only |
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