Mouse NMB Recombinant Protein (N-His-SUMO) (MY149012)

Name: Mouse NMB Recombinant Protein (N-His-SUMO)
Brand: abinScience
SKU: MY149012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MY149012
Description	Recombinant Mouse NMB Protein, N-His-SUMO (MY149012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q9CR53
Longueur de protéine	Asn28-Arg78
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Neuromedin-B, Neuromedin-B-32, Nmb
Contexte	Neuromedin-B is a ~13 kDa protein. Stimulates smooth muscle contraction. Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem. These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneeze reflex. Contributes to induction of acute itch, possibly through activation of the NMBR receptor on dorsal root ganglion neurons. 1. Li, P. et al. (2016) Nature 530, 293-297. PMID: 26855425 2. Li, F. et al. (2021) Cell 184, 3762-3773.e10. PMID: 34133943 3. Ehling, S. et al. (2019) Acta dermato-venereologica 99, 587-893. PMID: 30734045 4. Yang, G. et al. (2019) Veterinary research 50, 80. PMID: 31601264 5. Yeo, CE. et al. (2017) Experimental cell research 359, 112-119. PMID: 28780306
Note	For research use only

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Mouse NMB Recombinant Protein (N-His-SUMO).pdf

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