Mouse Integrin beta 3/CD61 Recombinant Protein (N-His) (MY323012)

Name: Mouse Integrin beta 3/CD61 Recombinant Protein (N-His)
Brand: abinScience
SKU: MY323012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MY323012
Description	Mouse Integrin beta 3/CD61 Recombinant Protein (N-His) (MY323012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE. by SDS-PAGE. Highlights ●Recombinant — Consistent lot-to-lot performance. ●High Purity — >90% as determined by SDS-PAGE. by SDS-PAGE for demanding downstream applications.
Système d'expression	E. coli
Numéro d'accès	O54890
Longueur de protéine	Pro136-Ser378
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CD61, GP3A, GPIIIa, ITGB3, Integrin beta-3, Platelet membrane glycoprotein IIIa
Contexte	Integrin beta-3 (Integrin αVβ3 (CD51/ITGAV & CD61) is a ~87 kDa protein. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. 1. Si-Tahar, M. et al. (1997) The Journal of biological chemistry 272, 11636-47. PMID: 9111081 2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 3. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099 4. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 5. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324 6. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677 7. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119 8. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464 9. Takada, YK. et al. (2017) The Journal of biological chemistry 292, 20067-20075. PMID: 29030430 10. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536
Note	For research use only

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Mouse Integrin beta 3/CD61 Recombinant Protein (N-His).pdf

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