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InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A) (VK681070)

InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A)
InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A)
価格(USD): $
スペック:
  • 100ug
  • 1mg
数量:
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概要
カタログ番号VK681070
説明
InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A) [AR4A] (VK681070) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
種反応性Hepatitis C virus genotype 1a (isolate H77) (HCV)
アプリケーションELISA, Neutralization
宿主種Human
アイソタイプIgG1
クローンIDAR4A
クローン性 Monoclonal
ターゲット Genome polyprotein, Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P27958
RRID InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A) (abinScience Cat# VK681070, RRID:AB_3729572)
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Genome polyprotein (E1 & E2 (gp35 & gp70)) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802
2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612
3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025
4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511
5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
注意事項 For research use only. Not suitable for clinical or therapeutic use.
イメージ
  • InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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