

| Numéro de catalogue | HV139014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-A1CF Polyclonal Antibody (HV139014) is a rabbit polyclonal antibody detecting A1CF in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human A1CF (Gly389-Arg587). | ||||||||
| Cible | ACF, ASP, APOBEC1 complementation factor, A1CF, APOBEC1-stimulating protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9NQ94 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | APOBEC1 complementation factor (A1CF) is a ~65 kDa protein. Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. | ||||||||
| Note | For research use only. |
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