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| カタログ番号 | HV453014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ABCB9 (Val504-Ala766). | ||||||||
| ターゲット | ATP-binding cassette transporter 9, ABC transporter 9 protein, ATP-binding cassette sub-family B member 9, hABCB9, TAP-like protein, ABCB9, KIAA1520, TAPL | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9NP78 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ABC-type oligopeptide transporter ABCB9 is a ~84 kDa protein. ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen for degradation. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Binds and transports smaller and larger peptides with the same affinity. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. 1. Wolters, JC. et al. (2005) The Journal of biological chemistry 280, 23631-6. PMID: 15863492 2. Demirel, O. et al. (2007) The Journal of biological chemistry 282, 37836-43. PMID: 17977821 3. Zhao, C. et al. (2008) The Journal of biological chemistry 283, 17083-91. PMID: 18434309 4. Demirel, Ö. et al. (2012) Journal of cell science 125, 4230-40. PMID: 22641697 5. Zollmann, T. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 2046-51. PMID: 25646430 6. Bock, C. et al. (2018) Scientific reports 8, 15662. PMID: 30353140 7. Graab, P. et al. (2019) The Journal of biological chemistry 294, 7308-7323. PMID: 30877195 8. Bock, C. et al. (2019) Scientific reports 9, 11884. PMID: 31417173 | ||||||||
| 注意事項 | For research use only. |
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