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Anti-ABCD3 Polyclonal Antibody (HB262014)

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Aperçu
Numéro de catalogueHB262014
Description
Anti-ABCD3 Polyclonal Antibody (HB262014) is a rabbit polyclonal antibody detecting ABCD3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human ABCD3 (Pro425-Ser659).
Cible ABCD3, 70 kDa peroxisomal membrane protein, ATP-binding cassette sub-family D member 3, PXMP1, PMP70
Purification Purified by antigen affinity column.
Numéro d'accès P28288
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

ATP-binding cassette sub-family D member 3 (ABCD3) is a ~75 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation.

1. Roerig, P. et al. (2001) FEBS letters 492, 66-72. PMID: 11248239
2. van Roermund, CW. et al. (2014) Biochimica et biophysica acta 1841, 563-8. PMID: 24333844
3. Ferdinandusse, S. et al. (2015) Human molecular genetics 24, 361-70. PMID: 25168382
4. Okamoto, T. et al. (2018) Biochemical and biophysical research communications 496, 1122-1127. PMID: 29397936
5. Vaca Jacome, AS. et al. (2015) Proteomics 15, 2519-24. PMID: 25944712
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-ABCD3 Polyclonal Antibody

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