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Anti-ABCG1 Polyclonal Antibody (HW364014)

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Aperçu
Numéro de catalogueHW364014
Description
Anti-ABCG1 Polyclonal Antibody (HW364014) is a rabbit polyclonal antibody detecting ABCG1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human ABCG1 (Met1-His353).
Cible ATP-binding cassette transporter 8, ABC8, ATP-binding cassette sub-family G member 1, ABCG1, WHT1, White protein homolog
Purification Purified by antigen affinity column.
Numéro d'accès P45844
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

ATP-binding cassette sub-family G member 1 (ABCG1) is a ~75 kDa protein. Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.

1. Engel, T. et al. (2007) FEBS letters 581, 1673-80. PMID: 17408620
2. Gu, HM. et al. (2014) Biochimica et biophysica acta 1841, 847-58. PMID: 24576892
3. Kobayashi, A. et al. (2006) Journal of lipid research 47, 1791-802. PMID: 16702602
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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