

| Numéro de catalogue | HW364014 | ||||||||
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| Description |
Anti-ABCG1 Polyclonal Antibody (HW364014) is a rabbit polyclonal antibody detecting ABCG1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ABCG1 (Met1-His353). | ||||||||
| Cible | ATP-binding cassette transporter 8, ABC8, ATP-binding cassette sub-family G member 1, ABCG1, WHT1, White protein homolog | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P45844 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | ATP-binding cassette sub-family G member 1 (ABCG1) is a ~75 kDa protein. Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. 1. Engel, T. et al. (2007) FEBS letters 581, 1673-80. PMID: 17408620 2. Gu, HM. et al. (2014) Biochimica et biophysica acta 1841, 847-58. PMID: 24576892 3. Kobayashi, A. et al. (2006) Journal of lipid research 47, 1791-802. PMID: 16702602 | ||||||||
| Note | For research use only. |
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