

| Каталожный номер | HW364014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-ABCG1 Polyclonal Antibody (HW364014) is a rabbit polyclonal antibody detecting ABCG1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human ABCG1 (Met1-His353). | ||||||||
| Цель | ATP-binding cassette transporter 8, ABC8, ATP-binding cassette sub-family G member 1, ABCG1, WHT1, White protein homolog | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P45844 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | ATP-binding cassette sub-family G member 1 (ABCG1) is a ~75 kDa protein. Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. 1. Engel, T. et al. (2007) FEBS letters 581, 1673-80. PMID: 17408620 2. Gu, HM. et al. (2014) Biochimica et biophysica acta 1841, 847-58. PMID: 24576892 3. Kobayashi, A. et al. (2006) Journal of lipid research 47, 1791-802. PMID: 16702602 | ||||||||
| Примечание | For research use only. |
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