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| カタログ番号 | HB956014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ACADS Polyclonal Antibody (HB956014) is a rabbit polyclonal antibody detecting ACADS in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ACADS (Ile210-Glu396). | ||||||||
| ターゲット | ACADS, Short-chain specific acyl-CoA dehydrogenase, mitochondrial, Butyryl-CoA dehydrogenase, SCAD | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P16219 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADS) is a ~44 kDa protein. Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains. 1. Corydon, MJ. et al. (2001) Pediatric research 49, 18-23. PMID: 11134486 2. He, M. et al. (2011) Molecular genetics and metabolism 102, 418-29. PMID: 21237683 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-ACADS polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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