Anti-ACOX1 Polyclonal Antibody (HS771014)

Name: Anti-ACOX1 Polyclonal Antibody
Brand: abinScience
SKU: HS771014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HS771014

Description

Anti-ACOX1 Polyclonal Antibody (HS771014) is a rabbit polyclonal antibody detecting ACOX1 in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Human, Pongo abelii, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human ACOX1 (Tyr275-Leu660).

Cible

ACOX1, Palmitoyl-CoA oxidase, SCOX, AOX, ACOX, Peroxisomal acyl-coenzyme A oxidase 1, Straight-chain acyl-CoA oxidase

Purification

Purified by antigen affinity column.

Numéro d'accès

Q15067

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) is a ~74 kDa protein. Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)).

1. Ferdinandusse, S. et al. (2004) Journal of lipid research 45, 1104-11. PMID: 15060085

2. Ferdinandusse, S. et al. (2007) Human mutation 28, 904-12. PMID: 17458872

3. Oaxaca-Castillo, D. et al. (2007) Biochemical and biophysical research communications 360, 314-9. PMID: 17603022

4. Chung, HL. et al. (2020) Neuron 106, 589-606.e6. PMID: 32169171

5. Morita, A. et al. (2021) Brain & development 43, 475-481. PMID: 33234382

6. Chu, R. et al. (1995) The Journal of biological chemistry 270, 4908-15. PMID: 7876265

Note

For research use only.

Images

Reférences

Fiche technique

Anti-ACOX1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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