

| Numéro de catalogue | HW298014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-ACSL1 Polyclonal Antibody (HW298014) is a rabbit polyclonal antibody detecting ACSL1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ACSL1 (Gly457-Val698). | ||||||||
| Cible | FACL1, LACS2, Long-chain acyl-CoA synthetase 1, Long-chain acyl-CoA synthetase 2, Long-chain-fatty-acid--CoA ligase 1, ACS1, LACS 1, Palmitoyl-CoA ligase 2, Phytanate--CoA ligase, FACL2, Arachidonate--CoA ligase, Long-chain fatty acid-CoA ligase 2, ACSL1, Acyl-CoA synthetase 1, Palmitoyl-CoA ligase 1, LACS1, LACS, LACS 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P33121 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Long-chain-fatty-acid--CoA ligase 1 (ACSL1) is a ~77 kDa protein. Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs). 1. Golej, DL. et al. (2011) Journal of lipid research 52, 782-93. PMID: 21242590 2. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490 3. Ohkuni, A. et al. (2013) Biochemical and biophysical research communications 442, 195-201. PMID: 24269233 | ||||||||
| Note | For research use only. |
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