Anti-ACSL4 Polyclonal Antibody (HT115014)

Name: Anti-ACSL4 Polyclonal Antibody
Brand: abinScience
SKU: HT115014
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT115014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human ACSL4 (Lys500-Lys711).

Objetivo

ACS4, ACSL4, Long-chain-fatty-acid--CoA ligase 4, LACS 4, Arachidonate--CoA ligase, FACL4, Long-chain acyl-CoA synthetase 4, LACS4

Purificación

Purified by antigen affinity column.

Número de acceso

O60488

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Long-chain-fatty-acid--CoA ligase 4 (ACSL4) is a ~79 kDa protein. Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs. Modulates prostaglandin E2 secretion.

1. Golej, DL. et al. (2011) Journal of lipid research 52, 782-93. PMID: 21242590

2. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490

3. Ohkuni, A. et al. (2013) Biochemical and biophysical research communications 442, 195-201. PMID: 24269233

4. Shimbara-Matsubayashi, S. et al. (2019) Biological & pharmaceutical bulletin 42, 850-855. PMID: 31061331

5. Li, Z. et al. (2024) Nature chemical biology 20, 1341-1352. PMID: 38720107

6. Doll, S. et al. (2017) Nature chemical biology 13, 91-98. PMID: 27842070

7. Zhang, HL. et al. (2022) Nature cell biology 24, 88-98. PMID: 35027735

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-ACSL4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo