

| Número de catálogo | HF975014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-ADCY5 Polyclonal Antibody (HF975014) is a rabbit polyclonal antibody detecting ADCY5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ADCY5 (Ser1066-Ser1261). | ||||||||
| Objetivo | AC5, ATP pyrophosphate-lyase 5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY5 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O95622 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Adenylate cyclase type 5 (ADCY5) is a ~138 kDa protein. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. 1. Ding, Q. et al. (2004) Molecular pharmacology 66, 921-8. PMID: 15385642 2. Chen, YZ. et al. (2014) Annals of neurology 75, 542-9. PMID: 24700542 3. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 4. Hodson, DJ. et al. (2014) Diabetes 63, 3009-21. PMID: 24740569 | ||||||||
| Nota | For research use only. |
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